Ethnic Differences in the Brazilian Population Influence the Impact of BMP4 Genetic Variants on Susceptibility of Nonsyndromic Orofacial Clefts.

doi:10.1177/10556656231180086

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Article

Ethnic Differences in the Brazilian Population Influence the Impact of BMP4 Genetic Variants on Susceptibility of Nonsyndromic Orofacial Clefts.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Oct 2024

Rocha de Oliveira Lilianny Querino, de Souza Nicolau Hellen Carolliny, Barbosa Martelli Daniella Reis, Martelli-Júnior Hercílio, Scariot Rafaela, Ayroza Rangel Ana Lúcia Carrinho, de Almeida Reis Silvia Regina, Coletta Ricardo D, Machado Renato Assis

Abstract excerpt

OBJECTIVE: The study evaluated the association of BMP4 tag-SNPs and SNP-SNP interactions involving genes active by BMP4 pathway during craniofacial development in the susceptibility of nonsyndromic orofacial clefts (NSOC) in the Brazilian population. DESIGN: Case-control study. SETTING: Brazilian Oral Cleft Group. PARTICIPANTS: The study included 881 healthy controls and 800 patients with different types of NSOC:...

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Identifiers

PMID: 37272066
DOI: 10.1177/10556656231180086

Genes

BMP4
FGFR1
GREM1
NOG
VAX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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