Article
Studies with Wnt genes and nonsyndromic cleft lip and palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Nov 2010
Menezes Renato, Letra Ariadne, Kim Ana H, Küchler Erika C, Day Alicia, Tannure Patricia N, Gomes da Motta Luise, Paiva Katiucia B S, Granjeiro Jose M, Vieira Alexandre R
Abstract excerpt
BACKGROUND: Clefts of the lip and/or palate (cleft lip/palate) are notable for their complex etiology. The WNT pathway regulates multiple developmental processes including craniofacial development and may play a role in cleft lip/palate and other defects of craniofacial development such as tooth agenesis. Variations in WNT genes have been recently associated with cleft lip/palate in humans. In addition, two WNT...
Topics
- Brazil
- Case-Control Studies
- Cleft Lip
- Cleft Palate
- Dental Enamel Hypoplasia
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Phenotype
- Polymorphism, Single Nucleotide
