Article

Sleep chart of biological aging clocks across organs and omics

2025-08-11

Abstract excerpt

Optimal sleep plays a vital role in promoting healthy aging and enhancing longevity. This study proposes a Sleep Chart to assess the relationship between sleep duration and 23 biological aging clocks across 17 organ systems or tissues and 3 omics data types (imaging, proteomics, and metabolomics). First, a systemic, U-shaped pattern shows that both short (<6 hours) and long (>8 hours) sleep duration are linked to...

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Literature Corpus work: aeee07e2-cfe4-5e05-9ff3-f80bf56115e3
DOI: 10.1101/2025.08.08.25333313

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