Article
First detection of a putative knockdown resistance gene in major mosquito vector, Aedes albopictus.
Japanese journal of infectious diseases - 1 Jan 2011
Kasai Shinji, Ng Lee Ching, Lam-Phua Sai Gek, Tang Choon Siang, Itokawa Kentaro, Komagata Osamu, Kobayashi Mutsuo, Tomita Takashi
Abstract excerpt
The Asian tiger mosquito, Aedes albopictus (Skuse), is the major vector of Chikungunya fever and the secondary vector of dengue fever. We collected Ae. albopictus from Singapore and performed genotyping assay to detect mutations of the voltage-gated sodium channel, which is the target site of pyrethroid insecticides. We detected an amino acid substitution, F1534C, which is suspected to confer knockdown resistance...
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