Article
Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids.
Insect biochemistry and molecular biology - 1 Aug 2020
Yan Ru, Zhou Qiaoling, Xu Zhanyi, Zhu Guonian, Dong Ke, Zhorov Boris S, Chen Mengli
Abstract excerpt
Voltage-gated sodium channels are the major targets of several classes of insecticides, including pyrethroids. However, sensitivities of many insect pest species to pyrethroids have gradually decreased due to overuse in pest management programs. One major mechanism of pyrethroid resistance known as knockdown resistance (kdr) involves mutations in the sodium channel gene. Three new mutations in helix IIIS6 of...
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