Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Navigating the future of retinitis pigmentosa treatments: A comprehensive analysis of therapeutic approaches in rd10 mice

8 Feb 2024

Abstract excerpt

Retinitis pigmentosa (RP) is a degenerative disease, caused by genetic mutations that lead to a loss in photoreceptors. For research on RP, rd10 mice, which carry mutations in the phosphodiesterase (PDE) gene, exhibit degenerative patterns comparable to those of patients with RP, making them an ideal model for investigating potential treatments. Although numerous studies have reported the potential of biochemical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Photoreceptor and optogenetics research
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38341159
DOI: 10.1016/j.nbd.2024.106436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Navigating the future of retinitis pigmentosa treatments: A comprehensive analysis of therapeutic approaches in rd10 micePMID 38341159Read ↗

Review: the history and role of naturally occurring mouse models with Pde6b mutations.Semantic proximity Read ↗

AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.Semantic proximity Read ↗

HDAC inhibition ameliorates cone survival in retinitis pigmentosa miceSemantic proximity Read ↗

AAV8-PDE6B with 3’UTR provides durable rescue of photoreceptor structure and function in rd10 mouse model of retinitis pigmentosaSemantic proximity Read ↗

Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosaSemantic proximity Read ↗

Identifying a role for oxytosis/ferroptosis in Pde6b-associated retinitis pigmentosa.Semantic proximity Read ↗

HDAC inhibition ameliorates cone survival in retinitis pigmentosa miceSemantic proximity Read ↗

<i>In vivo</i> base editing rescues photoreceptors in a mouse model of retinitis pigmentosaSemantic proximity Read ↗

The New Era of Therapeutic Strategies for the Treatment of Retinitis Pigmentosa: From Pathomolecular Mechanisms to the Development of Cell-Based TherapiesSemantic proximity Read ↗

AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa.Semantic proximity Read ↗

Proteomics identifies multiple retinitis pigmentosa associated proteins involved in retinal degeneration in a mouse model bearing a Pde6b mutation.Semantic proximity Read ↗

X-Linked Retinitis Pigmentosa Gene Therapy: Preclinical AspectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.