Article
Evaluation of the causal effects of immune cells on ischemic stroke: a Mendelian randomization study.
Frontiers in immunology - 1 Jan 2024
Wang Kunyu, Zhang Beilin, Li Min, Duan Hanying, Jiang Zhuoya, Gao Su, Chen Jing, Fang Shaokuan
Abstract excerpt
Background: Ischemic stroke (IS) is a cerebrovascular disease caused by various factors, and its etiology remains inadequately understood. The role of immune system dysfunction in IS has been increasingly recognized. Our objective was to evaluate whether circulating immune cells causally impact IS risk. Methods: We conducted two-sample Mendelian randomization analyses to evaluate the causal effects of 731 immune...
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