Article
Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci.
Biological psychiatry - 15 Jun 2007
Jain Mahim, Palacio Luis Guillermo, Castellanos F Xavier, Palacio Juan David, Pineda David, Restrepo Maria I, Muñoz Juan F, Lopera Francisco, Wallis Deeann, Berg Kate, Bailey-Wilson Joan E, Arcos-Burgos Mauricio, Muenke Maximilian
Abstract excerpt
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) comorbid with oppositional defiant disorder (ODD) or conduct disorder (CD) and substance abuse/dependence seems to represent a specific subset within the phenotypic ADHD spectrum. METHODS: We applied complex segregation and linkage analyses in a set of multigenerational families densely segregating ADHD comorbid with ODD, CD, alcohol abuse/dependence,...
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