Article
Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders.
Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Jul 2018
Du Rietz Ebba, Coleman Jonathan, Glanville Kylie, Choi Shing Wan, O'Reilly Paul F, Kuntsi Jonna
Abstract excerpt
BACKGROUND: A recent large-scale mega genome-wide association study identified, for the first time, genetic variants at 12 loci significantly associated with attention-deficit/hyperactivity disorder (ADHD). In this study we use a powerful polygenic approach, with polygenic scores derived from the genome-wide association study, to investigate the etiological overlap between ADHD and frequently co-occurring traits...
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