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Article

The influence of acute dopamine transporter inhibition on manic-, depressive-like phenotypes, and brain oxidative status in adult zebrafish.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Apr 2024

Canzian Julia, Borba João V, Ames Jaíne, Silva Rossano M, Resmim Cássio M, Pretzel Camilla W, Duarte Maria Cecília F, Storck Tamiris R, Mohammed Khadija A, Adedara Isaac A, Loro Vania L, Gerlai Robert, Rosemberg Denis B

Abstract excerpt

Functional changes in dopamine transporter (DAT) are related to various psychiatric conditions, including bipolar disorder (BD) symptoms. In experimental research, the inhibition of DAT induces behavioral alterations that recapitulate symptoms found in BD patients, including mania and depressive mood. Thus, developing novel animal models that mimic BD-related conditions by pharmacologically modulating the...

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PMID: 38325745
DOI: 10.1016/j.pnpbp.2024.110961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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