Article
Zebrafish models to study drug abuse-related phenotypes.
Reviews in the neurosciences - 1 Jan 2011
Stewart Adam, Wong Keith, Cachat Jonathan, Gaikwad Siddharth, Kyzar Evan, Wu Nadine, Hart Peter, Piet Valerie, Utterback Eli, Elegante Marco, Tien David, Kalueff Allan V
Abstract excerpt
Mounting evidence implicates the zebrafish (Danio rerio) as a promising model species for reward and addiction research. Modeling drug abuse-related behavior in both adult and larval zebrafish produced a wealth of clinically translatable data, also demonstrating their sensitivity to various drugs of abuse and the ability to develop tolerance. Several studies have also applied withdrawal paradigms to model the...
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