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Article

Behavioral Analysis of Dopaminergic Activation in Zebrafish and Rats Reveals Similar Phenotypes.

ACS chemical neuroscience - 18 May 2016

Ek Fredrik, Malo Marcus, Åberg Andersson Madelene, Wedding Christoffer, Kronborg Joel, Svensson Peder, Waters Susanna, Petersson Per, Olsson Roger

Abstract excerpt

Zebrafish is emerging as a complement to mammals in behavioral studies; however, there is a lack of comparative studies with rodents and humans to establish the zebrafish as a predictive translational model. Here we present a detailed phenotype evaluation of zebrafish larvae, measuring 300-3000 variables and analyzing them using multivariate analysis to identify the most important ones for further evaluations....

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PMID: 26947759
DOI: 10.1021/acschemneuro.6b00014

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