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Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission

5 Feb 2024

Abstract excerpt

Abstract Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study. Addressing this critical knowledge gap, we use the experimental medicine approach of immunomodulatory drug withdrawal in rheumatoid arthritis (RA) remission to synchronise flare processes allowing detailed...

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PMID: 38316770
DOI: 10.1038/s41467-024-45213-2

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