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Article

The predictive effect of family genetic risk scores as an indirect measure of causal effects of one disorder on another.

Psychological medicine - 1 Jun 2024

Kendler Kenneth S, Ohlsson Henrik, Sundquist Jan, Sundquist Kristina

Abstract excerpt

BACKGROUND: One potential cause of comorbidity is the direct causal effect of one disorder - A - on risk for subsequent onset of disorder B. Could genetic risk scores be utilized to test for such an effect? If disorder A causally impacts on risk for disorder B, then genetic risk for disorder A should be lower in cases of disorder A with v. without a prior onset of B. METHODS: In all individuals (n = 905 736) born...

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Identifiers

PMID: 38314515
DOI: 10.1017/S0033291723003847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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