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Article

Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample.

JAMA psychiatry - 1 Jul 2021

Kendler Kenneth S, Ohlsson Henrik, Sundquist Jan, Sundquist Kristina

Abstract excerpt

Importance: Family and genetic approaches have traditionally been used to evaluate our diagnostic concepts. Using a novel method, the family genetic risk score (FGRS), can we validate the genetic architecture of major affective and psychotic disorders in a national Swedish sample? Objective: To determine whether FGRSs, calculated for the entire Swedish population, can elucidate the genetic relationship between...

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Identifiers

PMID: 33881469
DOI: 10.1001/jamapsychiatry.2021.0336
PMCID: PMC8060884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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