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Article

The outcome of major psychiatric and substance use disorders as an index of genetic risk and genetic heterogeneity.

Psychological medicine - 14 Aug 2025

Kendler Kenneth S, Ohlsson Henrik, Sundquist Jan, Sundquist Kristina

Abstract excerpt

BACKGROUND: We investigate whether, in Swedish national registers, social and psychiatric outcomes for six major psychiatric and substance disorders - drug use disorder (DUD), alcohol use disorder (AUD), major depression (MD), bipolar disorder (BD), anxiety disorder (AD), and schizophrenia (SZ) - reflect the primary genetic risk for each disorder and the level of genetic heterogeneity. METHODS: We utilize Genetic...

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Identifiers

PMID: 40810310
DOI: 10.1017/S0033291725101116
PMCID: PMC12360690

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