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Article

Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice.

Molecular neurobiology - 1 Sept 2024

Zhong Juan, He Yingxi, Zhao Qin, Luo Haodong, Zhang Qing, Tian Yu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Pan Lu, Tan Botao

Abstract excerpt

Spinal cord injury (SCI) results in stalled motor function recovery under the chronic phase. One of the reasons due to the presence of ongoing inflammation. Therefore, regulating the status of immune cells may help reopen the window for neural repair, which represents a potential therapeutic target. In this study, we aimed to investigate whether this could be achieved in mice with cervical 5 crush CSCI (4 W) by...

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PMID: 38311654
DOI: 10.1007/s12035-024-03979-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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