Article
The Degree of Cardiovascular Autonomic Dysfunction is not Different in GBA-Related and Idiopathic Parkinson's Disease Patients: A Case-Control Instrumental Evaluation.
Journal of Parkinson's disease - 1 Jan 2024
Giannini Giulia, Minardi Raffaella, Barletta Giorgio, Cani Ilaria, Cecere Annagrazia, Baldelli Luca, Fiorentino Alessia, Guaraldi Pietro, Sambati Luisa, Capellari Sabina, Cortelli Pietro, Carelli Valerio, Calandra-Buonaura Giovanna
Abstract excerpt
Background: Increased prevalence of cardiovascular autonomic failure might play a key role on Parkinson's disease (PD) progression of glucocerebrosidase gene (GBA)-mutated patients, determining a malignant phenotype of disease in these patients. Objective: To objectively characterize, for the first time, the cardiovascular autonomic profile of GBA-mutated patients compared to idiopathic PD patients by means of...
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