Article
Comparison of disease progression between brain-predominant Parkinson's disease versus Parkinson's disease with body-involvement phenotypes.
Neurobiology of disease - 1 Nov 2022
Ryu Dong-Woo, Yoo Sang-Won, Oh Yoon-Sang, Lee Kwang-Soo, Ha Seunggyun, Kim Joong-Seok
Abstract excerpt
Recently, new disease phenotyping has been proposed based on the origin site of α-synuclein pathology in Parkinson's disease (PD). In addition, a great deal of evidences suggested of parallel degeneration in the central nervous system and peripheral nervous system in PD. The myocardial uptake pattern of 123I-meta-iodobenzylguanidine can be a surrogate imaging biomarker for the peripheral nervous system...
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