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[The clinical features of Parkinson's disease in patients with mutations and polymorphic variants of GBA gene].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2000

Senkevich K A, Miliukhina I V, Beletskaia M V, Gracheva E V, Kudrevatykh A V, Nikolaev M A, Emelyanov A K, Kopytova A E, Timofeeva A A, Yakimovskii A F, Pchelina S N

Abstract excerpt

BACKGROUND: Mutations in the glucocerebrosidase gene (GBA) increase the risk of Parkinson's disease (PD) by 6-10 times in all populations and are associated with the early-onset of PD, development of cognitive impairment and presence of psychotic disorders. At the same time, polymorphic variants associated with the twofold increase in the risk of PD were also described in the GBA gene. AIM: To estimate the...

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PMID: 29171494
DOI: 10.17116/jnevro201711710181-86

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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