Article
Genetics unravels protein-metabolite relationships.
Trends in endocrinology and metabolism: TEM - 1 Mar 2024
Hilser James R, Lusis Aldons J, Allayee Hooman
Abstract excerpt
Integrating molecular traits into genetic studies enhances our understanding of how DNA variation influences complex clinical and physiological phenotypes. In a recent article, Benson and colleagues apply this systems genetics approach with proteomics and metabolomics data in plasma from humans to identify and validate several previously unrecognized causal protein-metabolite associations.
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