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Article

Neurodevelopmental functions of CHD8: new insights and questions.

Biochemical Society transactions - 28 Feb 2024

Basson M Albert

Abstract excerpt

Heterozygous, de novo, loss-of-function variants of the CHD8 gene are associated with a high penetrance of autism and other neurodevelopmental phenotypes. Identifying the neurodevelopmental functions of high-confidence autism risk genes like CHD8 may improve our understanding of the neurodevelopmental mechanisms that underlie autism spectrum disorders. Over the last decade, a complex picture of pleiotropic CHD8...

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Identifiers

PMID: 38288845
DOI: 10.1042/BST20220926
PMCID: PMC10903457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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