Article
Risk factors for celiac disease.
Italian journal of pediatrics - 14 Aug 2015
Sarno Marco, Discepolo Valentina, Troncone Riccardo, Auricchio Renata
Abstract excerpt
Celiac Disease (CD) is an immune-mediated systemic disorder elicited by gluten and related prolamines in genetically susceptible individuals and it is the result of the interaction between genetic and environmental factors. Among genetic risk factors, the strongest association is with the HLA class II DQ region; nevertheless at least 39 non-HLA loci are associated with CD. Gluten is the main environmental trigger...
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