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Single nucleotide polymorphisms and Zn transport by ZIP11 shape functional phenotypes of HeLa cells.

Metallomics : integrated biometal science - 7 Feb 2024

Kim Elizabeth Y, Verdejo-Torres Odette, Diaz-Rodriguez Karla, Hasanain Farah, Caromile Leslie, Padilla-Benavides Teresita

Abstract excerpt

Zinc (Zn) is a vital micronutrient with essential roles in biological processes like enzyme function, gene expression, and cell signaling. Disruptions in the cellular regulation of Zn2+ ions often lead to pathological states. Mammalian Zn transporters, such as ZIP11, play a key role in homeostasis of this ion. ZIP11 resides predominately in the nucleus and Golgi apparatus. Our laboratory reported a function of...

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PMID: 38285610
DOI: 10.1093/mtomcs/mfae006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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