Article
The Influence of HLA Polymorphisms on the Severity of COVID-19 in the Romanian Population.
International journal of molecular sciences - 22 Jan 2024
Vică Mihaela Laura, Dobreanu Minodora, Curocichin Ghenadie, Matei Horea Vladi, Bâlici Ștefana, Vușcan Mihaela Elvira, Chiorean Alin Dan, Nicula Gheorghe Zsolt, Pavel Mironescu Daniela Cristina, Leucuța Daniel Corneliu, Teodoru Cosmin Adrian, Siserman Costel Vasile
Abstract excerpt
In this study, we aimed to investigate whether specific HLA alleles found in patients from Romania and the Republic of Moldova were associated with the severity of COVID-19 infection and its associated mortality. We analyzed the HLA alleles at the -A, -B, -C, -DRB1, and -DQB1 loci in a cohort of 130 individuals with severe and extremely severe forms of COVID-19, including 44 individuals who died. We compared...
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