Article
The Search of Association of HLA Class I and Class II Alleles with COVID-19 Mortality in the Russian Cohort.
International journal of molecular sciences - 4 Feb 2023
Cheranev Valery, Bulusheva Irina, Vechorko Valery, Korostin Dmitriy, Rebrikov Denis
Abstract excerpt
HLA genes play a pivotal role in the immune response via presenting the pathogen peptides on the cell surface in a host organism. Here, we studied the association of HLA allele variants of class I (loci A, B, C) and class II (loci DRB1, DQB1, DPB1) genes with the outcome of COVID-19 infection. We performed high-resolution sequencing of class HLA I and class II genes based on the sample population of 157 patients...
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