Article
HLA Polymorphisms and COVID-19 Susceptibility and Severity: Insights From an Iranian Patients Cohort.
Journal of cellular and molecular medicine - 1 May 2025
Hakimi Pooria, Zaboli Kasra Arbabi, Golbabapour-Samakoush Mohammadreza, Azizimohammadi Susan, Soleimani Fatemeh, Salmani Mohammad Hosein, Teimoori-Toolabi Ladan
Abstract excerpt
The HLA system is a crucial immune response component against infectious agents, including SARS-CoV-2. Certain polymorphisms may impart varying levels of protection or vulnerability to COVID-19. This research aims to understand the possible relationship between HLA polymorphisms and the susceptibility to COVID-19 and its severity. We recruited 290 hospitalised Iranian COVID-19 patients (130 severe and 160...
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