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Article

HLA Allele Frequencies and Association with Severity of COVID-19 Infection in Northern Italian Patients.

Cells - 30 May 2022

Guerini Franca Rosa, Bolognesi Elisabetta, Lax Agata, Bianchi Luca Nicola Cesare, Caronni Antonio, Zanzottera Milena, Agliardi Cristina, Albergoni Maria Paola, Banfi Paolo Innocente, Navarro Jorge, Clerici Mario

Abstract excerpt

HLA allelic distribution was analysed in a cohort of 96 Northern Italian subjects (53M/43F) (mean age 59.9 ± 13.3 years) from Lombardy who developed COVID-19 during the first two pandemic waves to investigate possible correlations between HLA molecules and disease severity. An important role of HLA- B and HLA-C loci in modulating the clinical severity of COVID-19 disease was identified. In particular, the HLA-B07...

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Identifiers

PMID: 35681490
DOI: 10.3390/cells11111792
PMCID: PMC9179900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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