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Probenecid Inhibits Influenza A(H5N1) and A(H7N9) Viruses In Vitro and in Mice

19 Jan 2024

Abstract excerpt

Avian influenza (AI) viruses cause infection in birds and humans. Several H5N1 and H7N9 variants are highly pathogenic avian influenza (HPAI) viruses. H5N1 is a highly infectious bird virus infecting primarily poultry, but unlike other AIs, H5N1 also infects mammals and transmits to humans with a case fatality rate above 40%. Similarly, H7N9 can infect humans, with a case fatality rate of over 40%. Since 1996,...

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PMID: 38275962
DOI: 10.3390/v16010152

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