Article

4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses

2022-11-07

Abstract excerpt

Influenza outbreaks are associated with substantial morbidity, mortality and economic burden. Next generation antivirals are needed to treat seasonal infections and prepare against zoonotic spillover of avian influenza viruses with pandemic potential. Having previously identified oral efficacy of the nucleoside analog 4’-Fluorouridine (4’-FlU, EIDD-2749) against SARS-CoV-2 and respiratory syncytial virus, we explo...

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Literature Corpus work: c5c52091-4b92-5957-b21f-dfe0d68ce7b3
DOI: 10.1101/2022.11.05.515296

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