Verdinexor, a Novel Selective Inhibitor of Nuclear Export, Reduces Influenza A Virus Replication<i>In Vitro</i>and<i>In Vivo</i>

Abstract excerpt

UNLABELLED: Influenza is a global health concern, causing death, morbidity, and economic losses. Chemotherapeutics that target influenza virus are available; however, rapid emergence of drug-resistant strains is common. Therapeutic targeting of host proteins hijacked by influenza virus to facilitate replication is an antiviral strategy to reduce the development of drug resistance. Nuclear export of influenza...

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