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Article

Long-term simulated microgravity fosters carotid aging-like changes via Piezo1.

Cardiovascular research - 30 Apr 2024

Zhang Jiaxin, Wang Xinpei, Fu Zihao, Xing Changyang, Wang Zhen, Yang Hongyan, Li Jiahui, Liu Meijie, Dong Ling, Zhang Xing, Li Yongzhi, Wang Jiaping, Long Jiangang, Liu Jiankang, Wang Shengpeng, Li Jia, Gao Feng

Abstract excerpt

AIMS: Elucidating the impacts of long-term spaceflight on cardiovascular health is urgently needed in face of the rapid development of human space exploration. Recent reports including the NASA Twins Study on vascular deconditioning and aging of astronauts in spaceflight are controversial. The aims of this study were to elucidate whether long-term microgravity promotes vascular aging and the underlying...

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Identifiers

PMID: 38271270
DOI: 10.1093/cvr/cvae024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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