Article
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
American journal of hematology - 1 Dec 2020
Tefferi Ayalew, Barbui Tiziano
Abstract excerpt
DISEASE OVERVIEW: Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms (MPN) respectively characterized by clonal erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus and risk of leukemic or fibrotic transformation. DIAGNOSIS: Bone marrow morphology remains the cornerstone of...
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