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Article

Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.

American journal of hematology - 1 Jan 2017

Tefferi Ayalew, Barbui Tiziano

Abstract excerpt

DISEASE OVERVIEW: Polycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus, and risk of leukemic or fibrotic transformation. DIAGNOSIS: PV is defined by a JAK2 mutation, whose absence, combined with...

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Source

Identifiers

PMID: 27991718
DOI: 10.1002/ajh.24607

Genes

JAK2
MPL
IDH2
ASXL1
CALR
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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