Article
KIR/HLA gene combinations influence susceptibility to B-cell chronic lymphocytic leukemia and the clinical course of disease.
Tissue antigens - 1 Aug 2011
Karabon L, Jedynak A, Giebel S, Wołowiec D, Kielbinski M, Woszczyk D, Kapelko-Slowik K, Kuliczkowski K, Frydecka I
Abstract excerpt
The aim of this study was to analyze the association between gene polymorphisms of killer-cell immunoglobulin-like receptors (KIRs) and their human leukocyte antigen (HLA) ligands and susceptibility to B-cell chronic lymphocytic leukemia (B-CLL) and the clinical course of disease. The distribution of individual KIR genes in 197 B-CLL patients and 200 controls was similar, except for a tendency for lower...
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