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Article

17q Gain in Neuroblastoma: A Review of Clinical and Biological Implications

12 Jan 2024

Abstract excerpt

Neuroblastoma (NB) is the most frequent extracranial solid childhood tumor. Despite advances in the understanding and treatment of this disease, the prognosis in cases of high-risk NB is still poor. 17q gain has been shown to be the most frequent genomic alteration in NB. However, the significance of this remains unclear because of its high frequency and association with other genetic modifications, particularly...

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PMID: 38254827
DOI: 10.3390/cancers16020338

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