Article
Regions syntenic to human 17q are gained in mouse and rat neuroblastoma.
Genes, chromosomes & cancer - 1 Jun 2004
Łastowska Maria, Chung Yeun-Jun, Cheng Ching Ngan, Haber Michelle, Norris Murray D, Kees Ursula R, Pearson Andrew D J, Jackson Michael S
Abstract excerpt
Gain of chromosome arm 17q is the most frequent chromosomal change in human neuroblastoma and is a powerful predictor of adverse outcome of disease. This suggests that the region of gain includes a gene or genes critical for tumor pathogenesis. Analyses of breakpoint positions have revealed that...
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