Article
Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 15 Jun 2001
Lastowska M, Cullinane C, Variend S, Cotterill S, Bown N, O'Neill S, Mazzocco K, Roberts P, Nicholson J, Ellershaw C, Pearson A D, Jackson M S
Abstract excerpt
PURPOSE: To determine the relationship between multiple genetic features, tumor morphology, and prognosis in neuroblastoma. PATIENTS AND METHODS: The genetic alterations and morphologic features that underpin three histopathologic risk classifications were analyzed in 108 neuroblastoma patients. Tumors were subdivided into four groups based on the three most frequent and prognostically significant genetic...
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