Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gain of Chromosome Arm 17q and Adverse Outcome in Patients with Neuroblastoma

24 Jun 1999

Abstract excerpt

BACKGROUND: Gain of genetic material from chromosome arm 17q (gain of segment 17q21-qter) is the most frequent cytogenetic abnormality of neuroblastoma cells. This gain has been associated with advanced disease, patients who are > or =1 year old, deletion of chromosome arm 1p, and amplification of the N-myc oncogene, all of which predict an adverse outcome. We investigated these associations and evaluated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroblastoma Research and Treatments
Share to Neuroendocrine Tumor Research Advances
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10379019
DOI: 10.1056/nejm199906243402504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gain of Chromosome Arm 17q and Adverse Outcome in Patients with NeuroblastomaPMID 10379019Read ↗

17q gain in neuroblastoma predicts adverse clinical outcomeSemantic proximity Read ↗

Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patientsSemantic proximity Read ↗

17q Gain in Neuroblastoma: A Review of Clinical and Biological ImplicationsSemantic proximity Read ↗

Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24.Semantic proximity Read ↗

Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progressionSemantic proximity Read ↗

Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progressionSemantic proximity Read ↗

Variety and complexity of chromosome 17 translocations in neuroblastomaSemantic proximity Read ↗

Allelic Loss of Chromosome 1p as a Predictor of Unfavorable Outcome in Patients with NeuroblastomaSemantic proximity Read ↗

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma.Semantic proximity Read ↗

Unequivocal Delineation of Clinicogenetic Subgroups and Development of a New Model for Improved Outcome Prediction in NeuroblastomaSemantic proximity Read ↗

Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors.Semantic proximity Read ↗

Molecular cytogenetic characterization of two non-MYCN amplified neuroblastoma cell lines with complex t(11;17).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.