Article
Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.
Journal of molecular endocrinology - 1 Apr 2015
Vandamme Timon, Peeters Marc, Dogan Fadime, Pauwels Patrick, Van Assche Elvire, Beyens Matthias, Mortier Geert, Vandeweyer Geert, de Herder Wouter, Van Camp Guy, Hofland Leo J, Op de Beeck Ken
Abstract excerpt
The human BON-1 and QGP-1 cell lines are two frequently used models in pancreatic neuroendocrine tumor (PNET) research. Data on the whole-exome genetic constitution of these cell lines is largely lacking. This study presents, to our knowledge, the first whole-exome profile of the BON-1 and QGP-1 cell lines. Cell line identity was confirmed by short tandem repeat profiling. Using GTG-banding and a CytoSNP-12v2...
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