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Article

Circulating Tumor DNA Profiling Identifies Actionable Mutations as Prognostic Markers in Advanced Neuroendocrine Tumors.

Neuroendocrinology - 1 Jan 2025

Zhou Na, Zhao Guofeng, Gao Yang, Xing Jiazhang, Wu Mingying, Ying Hongyan, Guan Mei, Wu Huanwen, Zhao Lin, Bai Chunmei, Cheng Yuejuan

Abstract excerpt

<p>Introduction: Neuroendocrine tumors (NETs) are a rare and heterogeneous group of neoplasms with both clinical and genetic diversity. The clinical applicability of molecular profiling using liquid biopsy for identifying actionable drug targets and prognostic indicators in patients with advanced NETs remains unclear. METHODS: In this study, we utilized a custom-made 37 genes panel of circulating tumor DNA...

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Aged
Biomarkers, Tumor
Circulating Tumor DNA
SETD2 gene
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuroendocrine Tumors

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Open in PubMed Open full text

Identifiers

PMID: 40924644
DOI: 10.1159/000548256
PMCID: PMC12503830

Genes

TERT
JAG2
KMT2C
NOTCH3
SETD2
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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