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Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up

10 Nov 2021

Abstract excerpt

Abstract Purpose: As noninvasive biomarkers are an important unmet need for neuroendocrine neoplasms (NEN), biomarker potential of genome-wide molecular profiling of plasma cell-free DNA (cfDNA) was prospectively studied in patients with NEN. Experimental Design: Longitudinal plasma samples were collected from patients with well-differentiated, metastatic gastroenteropancreatic and lung NEN. cfDNA was subjected...

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Cancer Genomics and Diagnostics
Lung Cancer Research Studies
Neuroendocrine Tumor Research Advances

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34759042
DOI: 10.1158/1078-0432.ccr-21-2291

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