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Article

The dynamic variation position and predominant quasispecies of hepatitis B virus: Novel predictors of early hepatocarcinoma.

Virus research - 1 Mar 2024

Zhang Chaojun, An Sanchun, Lv Ruibo, Li Kezhi, Liu Haizhou, Li Jilin, Tang Yanping, Cai Zhengmin, Huang Tianren, Long Long, Deng Wei

Abstract excerpt

To find the predictors of early HCC based on the dynamic changes of HBV quasispecies, this study utilizing the second-generation sequencing (NGS) and high-order multiplex droplet digital PCR (ddPCR) technology to examine the HBV quasispecies in serum of total 247 subjects recruited from high-incidence area of HCC. In the discovery stage, 15 non-synonymous Single Nucleotide Polymorphisms (SNPs) with higher variant...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Liver Neoplasms

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Share to Quasispecies

Source

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Identifiers

PMID: 38242020
DOI: 10.1016/j.virusres.2024.199317
PMCID: PMC10831745

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