Article
Compound heterozygosity induces a rare Gerbich-negative phenotype in an immunized blood donor.
Transfusion - 1 Feb 2024
Petermann Sarah, Mayer Vanessa, Carbol Alexander, Opitz Andreas, Flesch Brigitte K
Abstract excerpt
BACKGROUND: Antibodies to Gerbich blood group antigens are exceedingly rare and can cause moderate transfusion reactions. Several deletional variants of the GE-gene, that harbors long sequence repeats, enable alloimmunization and formation of naturally occurring antibodies. SUBJECT AND METHODS: A female blood donor and soldier of the German Army without history of pregnancy or transfusion showed an antibody...
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