Article
Genetic profiling of rat gliomas and cardiac schwannomas from life-time radiofrequency radiation exposure study using a targeted next-generation sequencing gene panel.
PloS one - 1 Jan 2024
Brooks Ashley M, Vornoli Andrea, Kovi Ramesh C, Ton Thai Vu T, Xu Miaofei, Mashal Ahmed, Tibaldi Eva, Gnudi Federica, Li Jian-Liang, Sills Robert C, Bucher John R, Mandrioli Daniele, Belpoggi Fiorella, Pandiri Arun R
Abstract excerpt
The cancer hazard associated with lifetime exposure to radiofrequency radiation (RFR) was examined in Sprague Dawley (SD) rats at the Ramazzini Institute (RI), Italy. There were increased incidences of gliomas and cardiac schwannomas. The translational relevance of these rare rat tumors for human disease is poorly understood. We examined the genetic alterations in RFR-derived rat tumors through molecular...
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