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Article

Environmental and sex-specific molecular signatures of glioma causation.

Neuro-oncology - 5 Jan 2022

Claus Elizabeth B, Cannataro Vincent L, Gaffney Stephen G, Townsend Jeffrey P

Abstract excerpt

BACKGROUND: The relative importance of genetic and environmental risk factors in gliomagenesis remains uncertain. METHODS: Using whole-exome sequencing data from 1105 adult gliomas, we evaluate the relative contribution to cancer cell lineage proliferation and survival of single-nucleotide mutations in tumors by IDH mutation subtype and sex. We also quantify the contributions of COSMIC cancer mutational...

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Identifiers

PMID: 33942853
DOI: 10.1093/neuonc/noab103
PMCID: PMC8730771

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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