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Mitochondrial DNA-Sensing Pathogen Recognition Receptors in Systemic Sclerosis-Associated Interstitial Lung Disease: a Review

8 Aug 2023

Abstract excerpt

Purpose of the review: Systemic sclerosis (SSc) is a condition of dermal and visceral scar formation characterized by immune dysregulation and inflammatory fibrosis. Approximately 90% of SSc patients develop interstitial lung disease (ILD), and it is the leading cause of morbidity and mortality. Further understanding of immune-mediated fibroproliferative mechanisms has the potential to catalyze novel treatment...

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Share to Inflammatory Myopathies and Dermatomyositis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38230363
DOI: 10.1007/s40674-023-00211-1

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