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Telomere dynamics in human pluripotent stem cells

17 Dec 2023

Abstract excerpt

Pluripotent stem cells (PSCs) are a promising source of stem cells for regenerative therapies. Stem cell function depends on telomere maintenance mechanisms that provide them with the proliferative capacity and genome stability necessary to multiply and regenerate tissues. We show here that established human embryonic stem cells (hESCs) have stable telomere length that is dependent on telomerase but not on...

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PMID: 38219218
DOI: 10.1080/15384101.2023.2285551

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