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The role of telomere-binding modulators in pluripotent stem cells

27 Jul 2019

Abstract excerpt

Pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs), ESCs derived by somatic cell nuclear transfer (ntESCs), and induced pluripotent stem cells (iPSCs) have unlimited capacity for self-renewal and pluripotency and can give rise to all types of somatic cells. In order to maintain their self-renewal and pluripotency, PSCs need to preserve their telomere length and homeostasis. In recent years,...

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PMID: 31350723
DOI: 10.1007/s13238-019-0651-y

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