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Article

C-X-C chemokine receptor type 5 gene polymorphism affects gene expression in CD4+ T cells and is associated with increased risk of colorectal cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014

Xing Junjie, Li Xu, Sui Jinke, Cao Guangwen, Fu Chuangang

Abstract excerpt

Dysregulation of the immune system may play important roles in the development of colorectal cancer (CRC). The C-X-C chemokine receptor type 5 (CXCR5) is one of the principal regulators for targeting T cells, B cells, and dendritic cells into secondary lymphoid organs. The current study investigated the association between CXCR5 gene polymorphisms and the risk of CRC, and the potential effect of these...

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Source

Identifiers

PMID: 24833093
DOI: 10.1007/s13277-014-2069-8

Genes

CXCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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